Ionic insertion fabrication of novel octacalcium phosphate block materials exhibiting antibacterial ability and biocompatibility

As the population ages worldwide, importance of maintaining metabolism skeletal system becomes increasingly important. The skeleton is core locomotor and oral structure. Moreover, infection control an essential part orthopedic surgery. This paper investigates new bone substitutes fabricated by ionic substitution method leading to octacalcium phosphate (OCP) with excellent contact antibacterial ability, biocompatibility, replacement. To improve functionality OCP-based materials as a substitute, we introduce novel OCP block fabrication based on dissolution–precipitation method, study factors that induce in solution, propose robust for cation unit lattice named insertion method. We then fabricate Ag-substituted (OCP–Ag) blocks using this evaluate their activity vivo. These techniques will contribute new-generation medical services quality life individuals requiring implants.